First-generation antihistamines, such as chlorpheniramine and hydroxyzine, remain effective in controlling severe allergic reactions. However, their CNS penetration and sedative effects often limit their use in day-to-day settings, particularly for working individuals and students.
In contrast, newer-generation antihistamines like Bilastine have become increasingly preferred for routine allergy management. With minimal penetration of the blood-brain barrier, Bilastine offers strong peripheral H1 receptor antagonism without the sedative burden making it ideal for patients who need to stay alert and functional during the day.
As pharmacists, recommending or dispensing Bilastine and other non-sedating antihistamines can improve compliance and quality of life, especially for individuals with allergic rhinitis, urticaria, or seasonal allergies.
While older antihistamines still have a place in more severe or acute cases, the shift toward modern agents reflects the growing demand for efficacy without compromise on daily performance.
Stay informed, and continue guiding patients to the right choice based on their lifestyle and allergy profile.
Regards,
JAKSTAR PHARMA,
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