1. Methylcobalamin 2500 µg Injection
   A high-dose form of vitamin B12 (methylcobalamin), typically given intramuscularly or subcutaneously at 2500 µg (2.5 mg).
   Indications include:

• Vitamin B12 deficiency (including pernicious anemia and megaloblastic anemia)
• Peripheral neuropathy, such as diabetic or alcoholic neuropathy.
• General neurological support: fatigue, memory issues, mood, and nerve function, especially where low B12 is a factor .

1. Combination Injections: Methylcobalamin + Nicotinamide (B3) + Pyridoxine (B6) & FOLIC ACID .
   A multi-B-vitamin injection containing:

• Methylcobalamin – for B12
• Nicotinamide – for B3
• Pyridoxine – for B6
• Often folic acid (B9) .
  Indications include:
• Prevention or correction of combined B vitamin deficiencies—B12, B3, B6 (and B9) .
• Peripheral neuropathies, especially diabetic or alcoholic neuropathy .
• Broader neurological benefits: cognitive disorders (e.g., dementia), cardiovascular health (homocysteine reduction), seizures, skin issues .
• With folic acid: anemias (megaloblastic) and nerve disorders .

Clinical Scenarios

• Isolated B12 deficiency / megaloblastic anemia / pernicious anemia → Use high-dose methylcobalamin injection.
• Diabetic neuropathy with suspected multiple B-vitamin deficiencies → Combo injection often preferred.
• Alcohol-related neuropathy, skin problems, cognitive decline, elevated homocysteine → Combo formulation offers broader benefit.
• Routine B12 shot in healthy individuals → Mono methylcobalamin injection suffices.

Highlights:

• Use Methylcobalamin 2500 µg when treating only B12-related issues like anemia, fatigue, nerve health.
• Choose Combo B12+B3+B6 injections when there’s multi-vitamin deficiency, complex neuropathy, metabolic concerns, or broader systemic needs.

Note: Both require medical supervision. Dosage and frequency depend on specific conditions and patient profile. Discuss with a healthcare provider for tailored therapy.
Regards ,
JAKSTAR PHARMA .