The B-complex group includes 8 essential vitamins, each with unique functions. However, not all are equally critical to supplement in daily life.

Most Pivotal B Vitamins for Human Health are:

1)Vitamin B12 (Cobalamin)
It is vital for Nerve function, red blood cell formation, DNA synthesis.People with high risk of deficiency are Vegetarians/vegans, Elderly,People with GI disorders (e.g., gastritis, post-bariatric surgery)
It often requires supplementation

2)Vitamin B9 (Folate/Folic Acid):
It is vital for DNA synthesis, pregnancy (prevents neural tube defects).It has high risk of deficiency in Pregnant women ,Individuals with anemia.
It is Commonly supplemented in women of reproductive age

3)Vitamin B6 (Pyridoxine):
It is vital for Brain health, mood regulation, nerve function. Its Deficiency risk are in Alcoholics and People on certain medications (e.g., isoniazid).
It is often included in nerve and energy supplements.

Now Vitamin Bs that rarely need Supplementation:
1)B2 (Riboflavin) – Easily obtained from dairy, eggs, leafy greens.
2)B5 (Pantothenic Acid) – Present in nearly all foods; deficiency is extremely rare.
3)B7 (Biotin) – Produced by gut flora; true deficiency is uncommon.

While all B vitamins are essential, B12, B9, and B6 are the most clinically important to monitor and supplement, especially in at-risk groups.
Others (like B2, B5, B7) are usually adequately obtained from a regular diet and rarely require supplementation.
This is a general information. For the supplementation it is required to see your physician.
Regards,
JAKSTAR PHARMA